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Center for Research in Biological Systems
University of California, San Diego
9500 Gilman Drive
La Jolla, CA 92093-0608, USA
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Search Results for
Alan Rick Horwitz
(10 results)
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Still Images
Video/Animation
Z-Stack
Time Series
CIL:25846
NCBI Organism Classification
Cricetulus griseus
Biological Process
focal adhesion disassembly
Cellular Component
focal adhesion
Time-lapse of a CHO.K1 cell cotransfected with very low levels of GFP-MIIA (myosin IIA, green) and paxillin (magenta). Yellow arrowheads mark paxillin-containing adhesions that disassemble concomitant...
CIL:9530
NCBI Organism Classification
Cricetulus griseus
Biological Process
negative regulation of cell adhesion involved in substrate-bound cell migration
Cellular Component
cell-substrate adherens junction
Adhesion dynamics in a migrating CHO K1 cell. CHO K1 cells expressing paxillin-mEGFP were plated onto coverslips that were preincubated with a solution of 5 ug/ml fibronectin overnight at 4o C. The ...
CIL:9968
NCBI Organism Classification
Mus musculus
Biological Process
motogenic signaling involved in postnatal olfactory bulb interneuron migration
Cellular Component
none specified
Migration of neuronal precursors along from the subventricular zone to the olfactory bulb via the rostral migratory stream. Parasagittal slices were prepared from P10 mice (see Webb et al.,PMID: 12071...
CIL:25845
NCBI Organism Classification
Cricetulus griseus
Biological Process
microtubule depolymerization
Cellular Component
myosin II complex
MT inhibition alters the location of the cell front. Time-lapse of a cell expressing RLC-D,D–GFP (a phospho-mimetic mutant of the RLC) on fibronectin in the presence of 1 mM nocodazole. Note the acc...
CIL:25847
NCBI Organism Classification
Cricetulus griseus
Biological Process
focal adhesion disassembly
Cellular Component
focal adhesion
6 MIIB inhibits adhesion turnover. Time-lapse of a CHO.K1 cell cotransfected with very low levels of GFP-MIIB (myosin IIB, green) and paxillin (magenta). Note that adhesions adjacent to MIIB-containin...
CIL:25844
NCBI Organism Classification
Cricetulus griseus
Biological Process
phospho-mimetic
Cellular Component
myosin II complex
Time-lapse microscopy of a spreading MIIB (myosin II B)-deficient cell cell expressing RLC-D,D–GFP (a phospho-mimetic mutant of the RLC) on fibronectin. Arrows point to clusters, or proto-bundles, d...
CIL:25843
NCBI Organism Classification
Cricetulus griseus
Biological Process
phospho-mimetic
Cellular Component
myosin regulatory light chain
CIL:37154
NCBI Organism Classification
Rattus
Biological Process
dendritic spine development
Cellular Component
dendritic spine
This is Video S1 and it corresponds to Figure 2A. It shows that local blebbistatin micropipetting, but not DMSO, increases spine formation and extension (arrowheads). Equal volumes of blebbistatin and...
CIL:37157
NCBI Organism Classification
Rattus
Biological Process
dendritic spine development
Cellular Component
dendritic spine
This is Video S2 which corresponds to still images in top row of Figure 2D. It shows the spine dynamics of control neurons. Time-lapse confocal imaging was performed on DIV14 hippocampal neurons co-ex...
CIL:37162
NCBI Organism Classification
Rattus
Biological Process
dendritic spine development
Cellular Component
dendritic spine
This is Video S3,which corresponds to still images in bottom row of Fig. 2D. It shows that knocking down levels of Myosin II B (MIIB) increases spine dynamics. Spines from MIIB knockdown neurons exten...